This RNAi was able to suppress the locomotion phenotypes found in L-AChR(gf) animals. L-AChR(gf) enhances synaptic activation of muscles by increasing L-AChR function.
"We found that the exposure of cells to an antioxidant (N-acetyl-L-cysteine; NAC) decreased the amount of nuclear COQ7 (Fig. 1f). The same treatment in worms reduced CLK-1-GFP nuclear localization (Fig. 1g)."
This RNAi was able to suppress the locomotion phenotypes found in L-AChR(gf) animals. L-AChR(gf) enhances synaptic activation of muscles by increasing L-AChR function.
This RNAi was able to suppress the locomotion phenotypes found in L-AChR(gf) animals. L-AChR(gf) enhances synaptic activation of muscles by increasing L-AChR function.
This RNAi was able to suppress the locomotion phenotypes found in L-AChR(gf) animals. L-AChR(gf) enhances synaptic activation of muscles by increasing L-AChR function.
This RNAi was able to suppress the locomotion phenotypes found in L-AChR(gf) animals. L-AChR(gf) enhances synaptic activation of muscles by increasing L-AChR function.
"Wild-type and par-3(ZF1) embryos both showed correct expression of an end-1::gfp transgene only in the E daughters (Fig. 2D,L), whereas par-3 embryos either lacked end-1::gfp expression or had faint expression in multiple cells (n=30) (Fig. 2H)."