"SRC-1 physically interacts with INA-1 intracellular domain in vitro and is colocalized with INA-1 in phagocytes to the pseudopods extending around apoptotic cells."; "SRC-1(Y416F) failed to interact with INA-1."
HLH-2 binding E-box sites are required for ina-1 expression in DTC. When mutated, ina-1p400M::GFP had GFP expression in only 7 4.2% (n = 185) of DTCs compared to nearly 100% expression in ina-1p400::GFP.
HLH-2 binding E-box sites are required for ina-1 expression in DTC. When mutated, ina-1p400M::GFP had GFP expression in only 7 4.2% (n = 185) of DTCs compared to nearly 100% expression in ina-1p400::GFP.
INA-1::GFP translational fusion, show diminishing GFP fluorescence between L4 and adult DTCs. INA-1 GFP is maintained throughout egglaying in the adult vab-3 mutants.