kap-1 : osm-3

Exacerbation of the osm-3 mutant phenotype (i.e. the specific loss of distal singlets) to produce the complete loss of sensory ciliary axonemes (Snow et al, 2004, Nat Cell Biol, 6, 1110; Evans et al, 2006, J. Cell Biol., 172, 663).

F20C5.11 : klp-11 : osm-3

Exacerbation of the osm-3 mutant phenotype (i.e. the specific loss of distal singlets) to produce the complete loss of sensory ciliary axonemes (Snow et al, 2004, Nat Cell Biol, 6, 1110; Evans et al, 2006, J. Cell Biol., 172, 663).

emb-9 : mig-6

Suppression of the phase 2 DTC defect was partial when RNAi was used to reduce EMB-9/collagen IV in mig-6(ev701) heterozygotes. Loss of precise DTC guidance along the DV axis of the lateral epidermis during the phase 2 migration is the phenotype of mig-6(ev701) heterozygous animals. Authors call this the class-s (class-short) defect as it is caused by disruption of the mig-6 short isoform. Migration is not slow as seen with the disruption of the long isoform. In wildtype, phase 1 migration comprises a longitudinal migration in opposite directions away from the mid-body using the ventral body muscle basement membrane as a substratum for migration. During phase 2, the DTCs turn and migrate across the lateral epidermal basement membrane towards the dorsal body wall muscles.