Ac-Asp-Glu binding

Binding to Ac-Asp-Glu.

serine-type D-Ala-D-Ala carboxypeptidase activity

Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.

zinc D-Ala-D-Ala carboxypeptidase activity

Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.

obsolete cerevisin activity

OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides.

obsolete regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway

OBSOLETE. Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway.

INTAC complex

A protein complex containing Integrator and protein phosphatase 2A core enzyme (PP2A-AC) that stably associates with the C-terminus of RNA polymerase II and promotes premature RNA polymerase II transcription termination.

ATF1-ATF4 transcription factor complex

Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.

obsolete caspase-1 activity

OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.

ATF4-CREB1 transcription factor complex

Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.

U12-type spliceosomal complex

Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.