pyrimidine dimer repair

The repair of UV-induced T-T, C-T and C-C dimers.

thymine/thymine mispair binding

Binding to a double-stranded DNA region containing a T/T mispair.

aclacinomycin T methylesterase activity

Catalysis of the reaction: aclacinomycin T(1+) + H2O = 15-demethylaclacinomycin T + methanol + H+.

photoreactive repair

The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.

T cell proliferation

The expansion of a T cell population by cell division. Follows T cell activation.

gamma-delta T cell differentiation

The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.

CD4-positive or CD8-positive, alpha-beta T cell lineage commitment

The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.

alpha-beta T cell differentiation

The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.

T-helper 17 cell lineage commitment

The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.

WICH complex

An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair.