- rft-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3).
- rft-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3).
- Ccdc166 [Search on AGR]
Homo sapiens ASSOCIATED WITH Arrhinencephaly; Brown-Vialetto-Van Laere syndrome 2; epidermolysis bullosa simplex with muscular dystrophy; INTERACTS WITH benzo[a]pyrene; bis(2-ethylhexyl) phthalate; perfluorohexanesulfonic acid
- Evc [Search on AGR]
Homo sapiens This gene encodes a protein containing a leucine zipper and a transmembrane domain. This gene has been implicated in both Ellis-van Creveld syndrome (EvC) and Weyers acrodental dysostosis. [provided by RefSeq, Jul 2008]
- Fam193a [Search on AGR]
Homo sapiens ASSOCIATED WITH cherubism; Ellis-Van Creveld syndrome; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; acrolein; Aflatoxin B2 alpha
- ifta-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in chemotaxis; intraciliary transport; and non-motile cilium assembly. Located in axoneme and ciliary basal body. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Is an ortholog of human WDR35 (WD repeat domain 35).
- Vang [Search on AGR]
Drosophila melanogaster Van Gogh (Vang) encodes a four-pass transmembrane protein that localizes to cell junctions. It is part of the Frizzled-dependent planar polarity pathway that establishes planar polarity in epithelia. It is also implicated in nervous system patterning.
- cdh-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Is an ortholog of human DCHS1 (dachsous cadherin-related 1) and DCHS2 (dachsous cadherin-related 2).
- Hgh1 [Search on AGR]
Homo sapiens ASSOCIATED WITH Arrhinencephaly; Brown-Vialetto-Van Laere syndrome 2; epidermolysis bullosa simplex with muscular dystrophy; INTERACTS WITH (-)-alpha-phellandrene; 3-isobutyl-1-methyl-7H-xanthine; acrylamide