Bma-syx-2

Brugia malayi

Predicted to be involved in vesicle-mediated transport. Predicted to be located in membrane. Is an ortholog of C. elegans syx-2. In C. elegans, syx-2 is involved in short-term memory.

Bma-hint-3

Brugia malayi

Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: HIT-like superfamily and Scavenger mRNA decapping enzyme C-term binding. Is an ortholog of C. elegans hint-3.

Bma-irk-3

Brugia malayi

Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion transport. Predicted to be located in membrane. Is an ortholog of C. elegans irk-3. In C. elegans, irk-3 is involved in short-term memory.

Bma-ist-1

Brugia malayi

Predicted to enable insulin receptor binding activity. Predicted to be involved in insulin receptor signaling pathway. Is an ortholog of C. elegans ist-1. In C. elegans, ist-1 is involved in dauer larval development; insulin receptor signaling pathway; and short-term memory.

Bma-unc-43

Brugia malayi

Predicted to enable ATP binding activity; calcium/calmodulin-dependent protein kinase activity; and calmodulin binding activity. Predicted to be involved in protein phosphorylation. Is an ortholog of C. elegans unc-43. In C. elegans, unc-43 is involved in MAPK cascade; medium-term memory; and positive regulation of gene expression.

Bma-magi-1

Brugia malayi

Enriched in digestive tract based on proteomic studies. Is predicted to encode a protein with the following domains: WW domain; PDZ superfamily; WW domain superfamily; and PDZ domain. Is an ortholog of C. elegans magi-1. In C. elegans, magi-1 is involved in habituation; long-term memory; and regulation of protein localization.

Bma-kin-2

Brugia malayi

Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans kin-2. In C. elegans, kin-2 is involved in medium-term memory; negative regulation of oocyte maturation; and regulation of establishment of cell polarity.

Bma-kvs-4

Brugia malayi

Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transport; protein homooligomerization; and transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Is an ortholog of C. elegans kvs-4. In C. elegans, kvs-4 is involved in long-term memory.

Bma-clu-1

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily; GSKIP domain superfamily; CLU domain containing protein; Tetratricopeptide repeat; Clustered mitochondria; Clustered mitochondria protein, N-terminal; CLU central domain; Mitochondrial function, CLU-N-term; CLU domain; and Translation initiation factor eIF3 subunit 135. Is an ortholog of C. elegans clu-1.

Bma-cpsf-3

Brugia malayi

Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term; Metallo-beta-lactamase; Zn-dependent metallo-hydrolase, RNA specificity domain; Beta-Casp domain; Zn-dependent metallo-hydrolase RNA specificity domain; Metallo-beta-lactamase superfamily domain; and Ribonuclease Z/Hydroxyacylglutathione hydrolase-like. Is an ortholog of C. elegans cpsf-3.