Predicted to enable molecular adaptor activity. Involved in several processes, including microtubule cytoskeleton organization; nematode larval development; and post-transcriptional regulation of gene expression. Located in cytoplasm. Part of CCR4-NOT complex. Expressed in germ line; gonad; and in male. Human ortholog(s) of this gene implicated in Vissers-Bodmer syndrome and holoprosencephaly 12. Is an ortholog of human CNOT1 (CCR4-NOT transcription complex subunit 1).
Is affected by several genes including drh-3; spn-4; and ogt-1 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies.
Is affected by several genes including drh-3; hpl-2; and spn-4 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies.
Is affected by several genes including etr-1; spn-4; and lpd-3 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound; Sirolimus; and allantoin based on microarray studies.
Is affected by several genes including drh-3; hpl-2; and spn-4 based on tiling array; RNA-seq; and microarray studies. Is affected by fluoranthene and adsorbable organic bromine compound based on microarray studies.
Predicted to enable mRNA binding activity. Predicted to be involved in nervous system development and regulation of alternative mRNA splicing, via spliceosome. Located in P granule. Expressed in several structures, including Psub4; Z2; Z3; germ line; and oocyte.
Is affected by several genes including rsr-2; spn-4; and hmg-3 based on tiling array and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and rifampin based on RNA-seq and microarray studies.