Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including maintenance of sister chromatid cohesion; nuclear division; and sexual reproduction. Located in several cellular components, including intracellular membrane-bounded organelle; metaphase plate; and microtubule cytoskeleton. Part of separase-securin complex. Is an ortholog of human ESPL1 (extra spindle pole bodies like 1, separase).
Enables protease binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including cortical granule exocytosis; maintenance of sister chromatid cohesion; and nuclear division. Located in condensed chromosome; cytoplasm; and spindle microtubule. Part of separase-securin complex. Expressed in germ cell.
Enables identical protein binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm. Expressed in head neurons and ventral nerve cord. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2D. Is an ortholog of human SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase).