sdc-3

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in mitotic sister chromatid segregation; negative regulation of transcription by RNA polymerase II; and sex determination. Located in X chromosome and nucleus. Expressed in germ line and oocyte.

her-1

Caenorhabditis elegans

Enables signaling receptor binding activity. Involved in male sex determination. Located in extracellular region.

dpy-21

Caenorhabditis elegans

Enables histone H4K20 demethylase activity. Predicted to be involved in chromatin remodeling. Located in X chromosome. Is an ortholog of human RSBN1L (round spermatid basic protein 1 like).

T14G8.6

Caenorhabditis elegans

Is affected by several genes including hsf-1; dpy-26; and sdc-3 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies.

H12C20.7

Caenorhabditis elegans

Is affected by sdc-3 based on RNA-seq studies. Is affected by Atrazine and nitroguanidine based on microarray studies.

dpy-26

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of condensin complex and dosage compensation complex. Expressed widely.

sdc-2

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in X chromosome and nuclear chromosome.

K02E7.4

Caenorhabditis elegans

Is affected by several genes including cyc-1; rsr-2; and sdc-3 based on microarray; tiling array; and RNA-seq studies. Is affected by rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). Human TNFAIP1 contributes to ubiquitin-protein transferase activity. Human TNFAIP1 enables identical protein binding activity and small GTPase binding activity.

xol-1

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome; mRNA alternative trans-splicing; and male sex determination. Predicted to be located in nucleus.

sdc-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome; negative regulation of transcription by RNA polymerase II; and sex determination. Located in X chromosome and nuclear chromosome.