Enriched in several structures, including VB1; anterior hypodermis; ciliated neurons; hermaphrodite somatic gonadal cell; and interfacial epithelial cell based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including
cyc-1;
nuo-6; and
numr-2 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; D-glucose; and stavudine based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in malaria. Is predicted to encode a protein with the following domains: Sushi/SCR/CCP domain; Sushi/SCR/CCP superfamily; Complement System Regulators and Virion Entry Mediators; and Sushi repeat (SCR repeat). Is an ortholog of human CR1 (complement C3b/C4b receptor 1 (Knops blood group)). Human CR1 enables complement receptor activity and opsonin binding activity.