rde-1

Caenorhabditis elegans

Enables DEAD/H-box RNA helicase binding activity; RNA endonuclease activity, producing 5'-phosphomonoesters; and siRNA binding activity. Involved in regulatory ncRNA-mediated heterochromatin formation and regulatory ncRNA-mediated post-transcriptional gene silencing. Part of RISC complex. Expressed in male.

K01G12.22

Caenorhabditis elegans

Is affected by adr-1; rde-3; and rrf-3 based on RNA-seq and microarray studies.

F33H2.3

Caenorhabditis elegans

Predicted to enable histone binding activity. Predicted to be located in nucleus. Is an ortholog of human ANP32A (acidic nuclear phosphoprotein 32 family member A); ANP32B (acidic nuclear phosphoprotein 32 family member B); and ANP32CP (acidic nuclear phosphoprotein 32 family member C, pseudogene).

T19H12.2

Caenorhabditis elegans

Predicted to enable histone binding activity. Predicted to be located in nucleus. Expressed in germ line. Is an ortholog of human ANP32B (acidic nuclear phosphoprotein 32 family member B); ANP32CP (acidic nuclear phosphoprotein 32 family member C, pseudogene); and ANP32E (acidic nuclear phosphoprotein 32 family member E).

W08F4.20

Caenorhabditis elegans

Is affected by several genes including lin-54; hda-2; and rde-3 based on RNA-seq and microarray studies.

daf-32

Caenorhabditis elegans

rde-2

Caenorhabditis elegans

Involved in meiotic chromosome segregation; regulatory ncRNA-mediated post-transcriptional gene silencing; and siRNA processing. Located in cytosol and mutator focus. Expressed in germ line.

Y39F10A.5

Caenorhabditis elegans

Is affected by rde-3 and rrf-3 based on microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies.

sri-41

Caenorhabditis elegans

Enriched in neurons based on microarray studies. Is affected by qui-1; rde-3; and eat-2 based on RNA-seq and microarray studies.

set-32

Caenorhabditis elegans

Predicted to enable histone H3 methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in chromatin.