T08G3.14

Caenorhabditis elegans

Is affected by nhr-49 based on RNA-seq studies.

egl-49

Caenorhabditis elegans

F31F7.9

Caenorhabditis elegans

Is affected by dpy-21; nhr-49; and let-767 based on RNA-seq studies.

C06H5.13

Caenorhabditis elegans

Is affected by daf-2 and nhr-49 based on microarray and RNA-seq studies.

max-5

Caenorhabditis elegans

mir-49

Caenorhabditis elegans

Is affected by several genes including prg-1; hrpk-1; and alg-1 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies.

unc-49

Caenorhabditis elegans

Predicted to enable GABA-A receptor activity. Predicted to contribute to chloride channel activity. Involved in gamma-aminobutyric acid signaling pathway; locomotory behavior; and regulation of backward locomotion. Located in neuromuscular junction and postsynaptic membrane. Expressed in AVA; anal sphincter muscle; body wall musculature; and somatic nervous system. Used to study epilepsy.

clec-49

Caenorhabditis elegans

Predicted to enable monosaccharide binding activity and signaling receptor activity. Predicted to be located in extracellular region.

sap-49

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and precatalytic spliceosome. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Nager acrofacial dysostosis; cervical cancer; and endocrine gland cancer (multiple). Is an ortholog of human SF3B4 (splicing factor 3b subunit 4).

his-49

Caenorhabditis elegans

Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4).