pro-1

Caenorhabditis elegans

Involved in germ cell development; gonad development; and rRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of nuclear pre-replicative complex and rixosome complex. Expressed widely. Is an ortholog of human WDR18 (WD repeat domain 18).

pro-2

Caenorhabditis elegans

Predicted to enable histone binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and ribosomal large subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Noc1p-Noc2p complex and Noc2p-Noc3p complex. Is an ortholog of human NOC2L (NOC2 like nucleolar associated transcriptional repressor).

col-181

Caenorhabditis elegans

Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Is an ortholog of human COL5A3 (collagen type V alpha 3 chain) and MARCO (macrophage receptor with collagenous structure).

Y48A6C.4

Caenorhabditis elegans

Predicted to be located in nucleus. Predicted to be part of MLL1 complex. Is an ortholog of human TEX10 (testis expressed 10).

gldi-1

Caenorhabditis elegans

Predicted to be involved in regulation of Notch signaling pathway. Predicted to be located in nucleolus. Is an ortholog of human NLE1 (notchless homolog 1).

nifk-1

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be located in nucleolus. Is an ortholog of human NIFK (nucleolar protein interacting with the FHA domain of MKI67).

znf-593

Caenorhabditis elegans

Predicted to enable zinc ion binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in cytoplasm and nucleus. Expressed in head. Is an ortholog of human ZNF593 (zinc finger protein 593).

homt-1

Caenorhabditis elegans

Predicted to enable N-terminal protein N-methyltransferase activity. Predicted to be involved in N-terminal protein amino acid methylation. Predicted to be located in cytoplasm. Expressed in PVT and uterus. Is an ortholog of human NTMT1 (N-terminal Xaa-Pro-Lys N-methyltransferase 1).

rbd-1

Caenorhabditis elegans

Predicted to enable RNA binding activity. Involved in several processes, including collagen and cuticulin-based cuticle development; positive regulation of growth rate; and vulval development. Located in nucleolus. Is an ortholog of human RBM19 (RNA binding motif protein 19).

Y48B6A.1

Caenorhabditis elegans

Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Is an ortholog of human BOP1 (BOP1 ribosomal biogenesis factor).