nuc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables deoxyribonuclease II activity. Involved in apoptotic DNA fragmentation. Acts upstream of or within with a positive effect on negative regulation of antimicrobial peptide production. Located in lysosome. Expressed in body wall musculature; head; intestinal cell; and vulva. Is an ortholog of human DNASE2 (deoxyribonuclease 2, lysosomal) and DNASE2B (deoxyribonuclease 2 beta).