ncl-1

Caenorhabditis elegans

Enables translation repressor activity. Involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of ribosome biogenesis; and nucleologenesis. Located in cytoplasm. Expressed in head and tail. Is an ortholog of human TRIM3 (tripartite motif containing 3).

nhl-1

Caenorhabditis elegans

Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Is an ortholog of human TRIM2 (tripartite motif containing 2).

Y47G6A.9

Caenorhabditis elegans

Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3G (RNA polymerase III subunit G) and POLR3GL (RNA polymerase III subunit GL).

rpc-25

Caenorhabditis elegans

Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3H (RNA polymerase III subunit H).

tftc-1

Caenorhabditis elegans

Predicted to enable DNA binding activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and transcription initiation at RNA polymerase III promoter. Predicted to be part of transcription factor TFIIIC complex. Is an ortholog of human GTF3C1 (general transcription factor IIIC subunit 1).

mafr-1

Caenorhabditis elegans

Predicted to enable RNA polymerase III core binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase III. Located in cytoplasm and nucleus. Expressed in hypodermis and intestine. Is an ortholog of human MAF1 (MAF1 homolog, negative regulator of RNA polymerase III).

W09C3.4

Caenorhabditis elegans

Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human POLR3F (RNA polymerase III subunit F).

tftc-5

Caenorhabditis elegans

Predicted to enable DNA binding activity. Predicted to contribute to RNA polymerase III type 1 promoter sequence-specific DNA binding activity and RNA polymerase III type 2 promoter sequence-specific DNA binding activity. Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIIC complex. Is an ortholog of human GTF3C5 (general transcription factor IIIC subunit 5).

ZC374.2

Caenorhabditis elegans

Enriched in PDA; dorso-rectal ganglion; intestine; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including nuo-6; atfs-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercuric chloride; rotenone; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Fibronectin type III; Immunoglobulin-like fold; Fibronectin type III domain; Striated Muscle Structural and Regulatory Protein; and Fibronectin type III superfamily.

F26E4.4

Caenorhabditis elegans

Predicted to enable DNA binding activity. Predicted to be involved in tRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex.