mgl-1

Caenorhabditis elegans

Predicted to enable group II metabotropic glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in nerve ring; neurons; and pharyngeal nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; attention deficit hyperactivity disorder; and autistic disorder. Is an ortholog of human GRM3 (glutamate metabotropic receptor 3).

mgl-2

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in several structures, including glutamatergic neurons; head neurons; pharyngeal nervous system; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 13 and spinocerebellar ataxia 44. Is an ortholog of human GRM1 (glutamate metabotropic receptor 1).

mgl-3

Caenorhabditis elegans

Predicted to enable adenylate cyclase inhibiting G protein-coupled glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in NSM; head neurons; and nerve ring. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; attention deficit hyperactivity disorder; and autistic disorder. Is an ortholog of human GRM8 (glutamate metabotropic receptor 8).

tsp-16

Caenorhabditis elegans

Predicted to be located in membrane. Is an ortholog of human UPK1B (uroplakin 1B).

eas-1

Caenorhabditis elegans

Involved in Golgi vesicle transport. Located in cis-Golgi network. Expressed widely. Is an ortholog of human GOLT1A (golgi transport 1A) and GOLT1B (golgi transport 1B).

zchc-1A

Caenorhabditis elegans

Predicted to enable zinc ion binding activity. Is an ortholog of human ZC2HC1A (zinc finger C2HC-type containing 1A) and ZC2HC1B (zinc finger C2HC-type containing 1B).

snt-1

Caenorhabditis elegans

Enables calcium ion binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Involved in several processes, including defecation; regulation of nematode pharyngeal pumping; and synaptic vesicle endocytosis. Located in synaptic vesicle. Expressed in several structures, including excretory gland cell; gonad; nervous system; pharyngeal gland cell; and rectal gland cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Is an ortholog of human SYT1 (synaptotagmin 1).

Y38H8A.4

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in spermatid development. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

C27D6.11

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in spermatid development. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

F32B5.1

Caenorhabditis elegans

Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to be located in extracellular space. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B).