Is affected by several genes including prg-1; mrps-5; and glh-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. Used to study Parkinson's disease.
Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and dauer larval development. Located in non-motile cilium and periciliary membrane compartment. Expressed in ASKL and ASKR.
Enables protein-folding chaperone binding activity. Involved in several processes, including chemical synaptic transmission; positive regulation of anterior/posterior axon guidance; and ventral cord development. Located in axon; basolateral plasma membrane; and somatodendritic compartment. Expressed in several structures, including excretory gland cell; hermaphrodite gonad; intestine; nervous system; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including Creutzfeldt-Jakob disease; Hirschsprung's disease; and generalized epilepsy with febrile seizures plus 9. Is an ortholog of human STX1A (syntaxin 1A).
Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and dauer larval development. Located in non-motile cilium and periciliary membrane compartment. Expressed in ASKL and ASKR.