jun-1

Caenorhabditis elegans

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit).

kgb-2

Caenorhabditis elegans

Predicted to enable JUN kinase activity. Predicted to be involved in JNK cascade. Predicted to be located in cytoplasm and nucleus.

Y51B9A.9

Caenorhabditis elegans

Predicted to enable JUN kinase activity. Predicted to be involved in JNK cascade. Predicted to be located in cytoplasm and nucleus.

C49C3.10

Caenorhabditis elegans

Predicted to enable JUN kinase activity. Predicted to be involved in JNK cascade. Predicted to be located in cytoplasm and nucleus.

eif-1.A

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human EIF1AX (eukaryotic translation initiation factor 1A X-linked) and EIF1AY (eukaryotic translation initiation factor 1A Y-linked).

her-1

Caenorhabditis elegans

Enables signaling receptor binding activity. Involved in male sex determination. Located in extracellular region.

Y54F10BM.13

Caenorhabditis elegans

Predicted to enable JUN kinase phosphatase activity. Predicted to be involved in regulation of JNK cascade. Predicted to be located in cytoplasm. Is an ortholog of human DUSP19 (dual specificity phosphatase 19).

eas-1

Caenorhabditis elegans

Involved in Golgi vesicle transport. Located in cis-Golgi network. Expressed widely. Is an ortholog of human GOLT1A (golgi transport 1A) and GOLT1B (golgi transport 1B).

arp-1

Caenorhabditis elegans

Part of dynactin complex. Human ortholog(s) of this gene implicated in Down syndrome and colon cancer. Is an ortholog of human ACTR1A (actin related protein 1A).

zchc-1A

Caenorhabditis elegans

Predicted to enable zinc ion binding activity. Is an ortholog of human ZC2HC1A (zinc finger C2HC-type containing 1A) and ZC2HC1B (zinc finger C2HC-type containing 1B).