ifb-1

Caenorhabditis elegans

Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including heterochromatin formation; nucleus organization; and protein localization to nuclear envelope. Located in apical plasma membrane. Expressed in several structures, including egg-laying apparatus; excretory system; pharyngeal-intestinal valve; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in partial lipodystrophy and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2).

tsp-16

Caenorhabditis elegans

Predicted to be located in membrane. Is an ortholog of human UPK1B (uroplakin 1B).

ifb-2

Caenorhabditis elegans

Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including heterochromatin formation; nucleus organization; and protein localization to nuclear envelope. Located in apical cortex; cell junction; and terminal web. Expressed in intestine. Human ortholog(s) of this gene implicated in partial lipodystrophy and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2).

eas-1

Caenorhabditis elegans

Involved in Golgi vesicle transport. Located in cis-Golgi network. Expressed widely. Is an ortholog of human GOLT1A (golgi transport 1A) and GOLT1B (golgi transport 1B).

zchc-1A

Caenorhabditis elegans

Predicted to enable zinc ion binding activity. Is an ortholog of human ZC2HC1A (zinc finger C2HC-type containing 1A) and ZC2HC1B (zinc finger C2HC-type containing 1B).

snt-1

Caenorhabditis elegans

Enables calcium ion binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Involved in several processes, including defecation; regulation of nematode pharyngeal pumping; and synaptic vesicle endocytosis. Located in synaptic vesicle. Expressed in several structures, including excretory gland cell; gonad; nervous system; pharyngeal gland cell; and rectal gland cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Is an ortholog of human SYT1 (synaptotagmin 1).

Y38H8A.4

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in spermatid development. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

C27D6.11

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in spermatid development. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

F32B5.1

Caenorhabditis elegans

Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to be located in extracellular space. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B).

W10C8.5

Caenorhabditis elegans

Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to be located in extracellular space. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B).