Predicted to enable metal ion binding activity. Acts upstream of or within with a positive effect on germ cell proliferation. Predicted to be located in cytoplasm; kinetochore; and spindle midzone. Predicted to be part of chromosome passenger complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endometrial hyperplasia; and steatotic liver disease (multiple). Is an ortholog of human BIRC2 (baculoviral IAP repeat containing 2); BIRC3 (baculoviral IAP repeat containing 3); and BIRC5 (baculoviral IAP repeat containing 5).
Predicted to enable metal ion binding activity. Involved in several processes, including chromosome organization; egg-laying behavior; and inductive cell migration. Located in condensed chromosome and spindle midzone. Part of chromosome passenger complex. Expressed in egg-laying apparatus; hypodermis; pharynx; rectal muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ductal carcinoma in situ; and endometrial hyperplasia. Is an ortholog of human BIRC5 (baculoviral IAP repeat containing 5).
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to be located in nucleus and trans-Golgi network. Is an ortholog of human BIRC6 (baculoviral IAP repeat containing 6).