Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane.
Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in cholinergic neurons and head neurons. Is an ortholog of human GRIK4 (glutamate ionotropic receptor kainate type subunit 4).
Is affected by several genes including prg-1; hrpk-1; and alg-1 based on RNA-seq studies. Is affected by four chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and nicotine based on RNA-seq studies.
Predicted to enable clathrin adaptor activity. Involved in positive regulation of locomotion. Located in synapse. Expressed in DD neuron; VD neuron; and cholinergic neurons. Is an ortholog of human STON2 (stonin 2).
Enables enzyme binding activity and glutamate-gated receptor activity. Involved in several processes, including forward locomotion; learning or memory; and positive regulation of locomotion. Located in several cellular components, including perinuclear endoplasmic reticulum; postsynapse; and somatodendritic compartment. Part of ionotropic glutamate receptor complex. Expressed in interneuron; neurons; and ventral nerve cord. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; childhood absence epilepsy; and intellectual disability (multiple). Is an ortholog of human GRIA2 (glutamate ionotropic receptor AMPA type subunit 2) and GRIA3 (glutamate ionotropic receptor AMPA type subunit 3).
Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in VC neuron and nerve ring neurons. Is an ortholog of human GRIK4 (glutamate ionotropic receptor kainate type subunit 4).
Enables mRNA binding activity and translation repressor activity. Involved in several processes, including negative regulation of gene expression; nematode male tail tip morphogenesis; and regulation of developmental process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and ribonucleoprotein granule. Expressed in several structures, including germ cell; hypodermal cell; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in hydrocephalus. Is an ortholog of human TRIM71 (tripartite motif containing 71).
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; neurons; and somatic nervous system.