Predicted to enable extracellular ligand-gated monoatomic ion channel activity and transmembrane signaling receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in postsynaptic membrane. Predicted to be part of chloride channel complex. Expressed in AIB; nerve ring neurons; and ventral cord neurons.
Predicted to enable extracellular ligand-gated monoatomic ion channel activity and transmembrane signaling receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Expressed in head neurons.
Predicted to enable extracellular ligand-gated monoatomic ion channel activity and transmembrane signaling receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Expressed in nerve ring and neurons.
Predicted to enable DNA binding activity; metal ion binding activity; and nuclease activity. Predicted to be located in nucleus. Used to study xeroderma pigmentosum. Human ortholog(s) of this gene implicated in several diseases, including cerebrooculofacioskeletal syndrome 3; respiratory system cancer (multiple); and xeroderma pigmentosum group G. Is an ortholog of human ERCC5 (ERCC excision repair 5, endonuclease).
Enables enzyme binding activity and identical protein binding activity. Involved in UV-damage excision repair and base-excision repair. Predicted to be located in nucleus. Predicted to be part of ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit).
Predicted to enable damaged DNA binding activity. Involved in several processes, including DNA repair; determination of adult lifespan; and response to UV-C. Located in nucleus. Used to study xeroderma pigmentosum. Human ortholog(s) of this gene implicated in xeroderma pigmentosum group A. Is an ortholog of human XPA (XPA, DNA damage recognition and repair factor).
Enables enzyme binding activity. Involved in DNA damage response; meiotic nuclear division; and regulation of multicellular organismal development. Predicted to be located in nucleus. Predicted to be part of nucleotide-excision repair factor 1 complex. Expressed in body wall musculature; embryonic cell; germ cell; and neurons. Used to study Cockayne syndrome; Fanconi anemia; and xeroderma pigmentosum group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia complementation group Q; XFE progeroid syndrome; and polyneuropathy due to drug. Is an ortholog of human ERCC4 (ERCC excision repair 4, endonuclease catalytic subunit).