Ovo-gap-2

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Ras GTPase-activating domain; GTPase-activator protein for Ras-like GTPase; Ras GTPase-activating protein; C2 domain; C2 domain superfamily; and Rho GTPase activation protein. Is an ortholog of C. elegans gap-2. In C. elegans, gap-2 is involved in learning or memory and negative regulation of Ras protein signal transduction.

OVOC7300

Onchocerca volvulus

Is predicted to encode a protein with the following domain: Integrin-alpha FG-GAP repeat-containing protein 2. Is an ortholog of B. malayi Bm10673.

OVOC8178

Onchocerca volvulus

Is predicted to encode a protein with the following domains: FG-GAP-like repeat and T-cell immunomodulatory protein. Is an ortholog of C. elegans lnkn-1.

Ovo-gap-1

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Ras GTPase-activating domain; PH domain; GTPase-activator protein for Ras-like GTPase; PH-like domain superfamily; Ras GTPase-activating protein; C2 domain superfamily; Rho GTPase activation protein; and Pleckstrin homology domain. Is an ortholog of C. elegans gap-1. In C. elegans, gap-1 is involved in chemosensory behavior; learning or memory; and negative regulation of Ras protein signal transduction.

Ovo-rbg-2

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Rab3GAP regulatory subunit, C-terminal; Rab3-GAP regulatory subunit, N-terminal; Rab3 GTPase-activating protein regulatory subunit N-terminus; Rab3GAP regulatory subunit; and Rab3 GTPase-activating protein regulatory subunit C-terminus. Is an ortholog of C. elegans rbg-2.

Ovo-polq-1

Onchocerca volvulus

Predicted to enable ATP binding activity; DNA binding activity; and DNA-directed DNA polymerase activity. Predicted to be involved in DNA-templated DNA replication. Is an ortholog of C. elegans polq-1. In C. elegans, polq-1 is involved in base-excision repair, gap-filling and cellular response to ionizing radiation.