Predicted to enable ligand-gated sodium channel activity. Involved in defecation and ultradian rhythm. Located in nuclear membrane and plasma membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3).
Is affected by several genes including ints-4; flr-4; and ilc-17.1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like.
Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 7. Is an ortholog of human COX6B1 (cytochrome c oxidase subunit 6B1).
Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 14. Is an ortholog of human COA3 (cytochrome c oxidase assembly factor 3).
Predicted to enable oxidoreductase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 16. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2).
Predicted to be involved in cilium assembly. Predicted to be located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital syndrome IV. Is an ortholog of human TCTN1 (tectonic family member 1) and TCTN3 (tectonic family member 3).