Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of condensin complex and dosage compensation complex. Expressed widely.
Is affected by several genes including hsf-1; dpy-26; and sdc-3 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies.
Is affected by several genes including dpy-26; sir-2.1; and ogt-1 based on RNA-seq and microarray studies. Is affected by cadmium and Sirolimus based on microarray studies.