dkf-1

Caenorhabditis elegans

Enables protein serine/threonine kinase activity. Involved in several processes, including defense response to Gram-positive bacterium; determination of adult lifespan; and positive regulation of protein import into nucleus. Acts upstream of or within with a positive effect on neuromuscular synaptic transmission. Located in several cellular components, including axon; cell cortex; and somatodendritic compartment. Expressed in neurons.

T22D1.5

Caenorhabditis elegans

Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex.

dkf-2

Caenorhabditis elegans

Enables protein homodimerization activity and protein serine/threonine kinase activity. Involved in defense response to bacterium; determination of adult lifespan; and signal transduction. Acts upstream of with a negative effect on protein import into nucleus. Located in cytoplasmic side of plasma membrane and cytosol. Part of serine/threonine protein kinase complex. Expressed in AVF; NSM; head neurons; lumbar neurons; and spermathecal-uterine junction. Human ortholog(s) of this gene implicated in congenital heart disease. Is an ortholog of human PRKD1 (protein kinase D1); PRKD2 (protein kinase D2); and PRKD3 (protein kinase D3).

T20D3.6

Caenorhabditis elegans

Predicted to be involved in mitochondrial respirasome assembly. Located in cytoplasm. Is an ortholog of human HIGD2A (HIG1 hypoxia inducible domain family member 2A).

tra-2

Caenorhabditis elegans

Enables transmembrane signaling receptor activity. Involved in developmental process involved in reproduction and oocyte fate determination. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. Expressed in germ line.

B0464.9

Caenorhabditis elegans

Predicted to enable protein C-terminal methylesterase activity and protein phosphatase 2A binding activity. Predicted to be involved in protein demethylation. Is an ortholog of human PPME1 (protein phosphatase methylesterase 1).

metl-2

Caenorhabditis elegans

Predicted to enable tRNA (cytidine-3-)-methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL2A (methyltransferase 2A, tRNA N3-cytidine) and METTL2B (methyltransferase 2B, tRNA N3-cytidine).

rsa-1

Caenorhabditis elegans

Enables protein phosphatase 2A binding activity. Involved in embryo development; mitotic spindle assembly; and protein localization to organelle. Located in centrosome. Part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Is an ortholog of human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma).

F47B8.3

Caenorhabditis elegans

Predicted to be located in mitochondrial matrix. Predicted to be part of protein phosphatase type 2A complex. Expressed in several structures, including GABAergic neurons; head muscle; head neurons; intestinal cell; and pharyngeal cell.

rsa-2

Caenorhabditis elegans

Enables beta-catenin binding activity and protein-macromolecule adaptor activity. Involved in embryonic digestive tract development; mitotic spindle organization; and protein localization to organelle. Located in centrosome. Part of protein phosphatase type 2A complex.