him-2

Caenorhabditis elegans

Y67A10A.7

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).

F38E9.1

Caenorhabditis elegans

Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Is an ortholog of human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2) and PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3).

sdc-2

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in X chromosome and nuclear chromosome.

sex-2

Caenorhabditis elegans

Acts upstream of or within primary sex determination and transcription by RNA polymerase II.

him-7

Caenorhabditis elegans

T24B8.7

Caenorhabditis elegans

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of protein stability. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in Y-linked spermatogenic failure 2; female-restricted syndromic X-linked intellectual disability 99; and non-syndromic X-linked intellectual disability 99. Is an ortholog of human USP24 (ubiquitin specific peptidase 24).

vha-20

Caenorhabditis elegans

Predicted to enable signaling receptor activity. Involved in nematode larval development and regulation of intracellular pH. Located in apical plasma membrane. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in X-linked parkinsonism-spasticity syndrome; congenital disorder of glycosylation type II; and syndromic X-linked intellectual disability Hedera type. Is an ortholog of human ATP6AP2 (ATPase H+ transporting accessory protein 2).

T14B4.3

Caenorhabditis elegans

Predicted to enable signaling receptor activity. Predicted to be involved in positive regulation of Wnt signaling pathway. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in X-linked parkinsonism-spasticity syndrome; congenital disorder of glycosylation type II; and syndromic X-linked intellectual disability Hedera type. Is an ortholog of human ATP6AP2 (ATPase H+ transporting accessory protein 2).

rbmx-2

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2 snRNP and precatalytic spliceosome. Is an ortholog of human RBMX2 (RNA binding motif protein X-linked 2).