cyn-6

Caenorhabditis elegans

Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B).

cyp-33E2

Caenorhabditis elegans

Enables monooxygenase activity. Involved in long-chain fatty acid metabolic process and regulation of nematode pharyngeal pumping. Located in intracellular membrane-bounded organelle. Expressed in pharynx. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8).

cyp-35A1

Caenorhabditis elegans

Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2D6 (cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)); and CYP2E1 (cytochrome P450 family 2 subfamily E member 1).

cyp-35A3

Caenorhabditis elegans

Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2D6 (cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)); and CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)).

cyp-14A3

Caenorhabditis elegans

Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; extrapyramidal and movement disease; and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1).

cyp-35A2

Caenorhabditis elegans

Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7).

cyp-35A5

Caenorhabditis elegans

Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine.

cyp-44A1

Caenorhabditis elegans

Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); diabetes mellitus (multiple); and lipid storage disease (multiple). Is an ortholog of human CYP24A1 (cytochrome P450 family 24 subfamily A member 1).

cps-6

Caenorhabditis elegans

Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrial intermembrane space. Is an ortholog of human ENDOG (endonuclease G).

cyp-14A5

Caenorhabditis elegans

Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in response to gamma radiation. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; extrapyramidal and movement disease; and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1).