cmk-1

Caenorhabditis elegans

Enables calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Involved in several processes, including neuron projection morphogenesis; positive regulation of transcription by RNA polymerase II; and thermosensory behavior. Located in cytoplasm and nucleus. Expressed in neurons and vulval muscle. Is an ortholog of human CAMK1 (calcium/calmodulin dependent protein kinase I).

chhy-1

Caenorhabditis elegans

Enables hexosaminidase activity. Involved in chondroitin sulfate catabolic process. Expressed in PLML; PLMR; head; intestinal cell; and vulva. Human ortholog(s) of this gene implicated in mucopolysaccharidosis IX. Is an ortholog of human HYAL2 (hyaluronidase 2).

asm-1

Caenorhabditis elegans

Enables sphingomyelin phosphodiesterase activity. Involved in ceramide biosynthetic process and sphingomyelin catabolic process. Located in extracellular region and lysosome. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1).

ckk-1

Caenorhabditis elegans

Enables calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Predicted to be involved in CAMKK-AMPK signaling cascade. Located in cytoplasm and nucleus. Expressed in head neurons; tail neurons; and vulval muscle. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1).

asm-2

Caenorhabditis elegans

Enables sphingomyelin phosphodiesterase activity. Involved in ceramide biosynthetic process and sphingomyelin catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1).

zyg-7

Caenorhabditis elegans

evl-7

Caenorhabditis elegans

mau-7

Caenorhabditis elegans

dhcr-7

Caenorhabditis elegans

Predicted to enable 7-dehydrocholesterol reductase activity. Predicted to be involved in cholesterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including Greenberg dysplasia; Pelger-Huet anomaly; and autoimmune disease (multiple). Is an ortholog of human DHCR7 (7-dehydrocholesterol reductase).

fer-7

Caenorhabditis elegans