golg-2

Caenorhabditis elegans

Predicted to be involved in Golgi organization. Predicted to be located in Golgi cis cisterna; Golgi cisterna membrane; and cis-Golgi network. Expressed in head ganglion; motor neurons; pharyngeal neurons; and tail neurons. Is an ortholog of human GOLGA2 (golgin A2).

fkb-1

Caenorhabditis elegans

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding; protein peptidyl-prolyl isomerization; and regulation of transcription by RNA polymerase II. Is an ortholog of human FKBP2 (FKBP prolyl isomerase 2).

pinn-1

Caenorhabditis elegans

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleus. Is an ortholog of human PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1).

Y57G11A.5

Caenorhabditis elegans

Predicted to enable mRNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in nuclear speck.

prp-21

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Is an ortholog of human SF3A1 (splicing factor 3a subunit 1).

fkb-2

Caenorhabditis elegans

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in sarcoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Graves' disease. Is an ortholog of human FKBP1A (FKBP prolyl isomerase 1A); FKBP1B (FKBP prolyl isomerase 1B); and FKBP1C (FKBP prolyl isomerase family member 1C).

Y17G9B.4

Caenorhabditis elegans

Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human PPID (peptidylprolyl isomerase D).

cyn-10

Caenorhabditis elegans

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human PPIL3 (peptidylprolyl isomerase like 3).

eas-1

Caenorhabditis elegans

Involved in Golgi vesicle transport. Located in cis-Golgi network. Expressed widely. Is an ortholog of human GOLT1A (golgi transport 1A) and GOLT1B (golgi transport 1B).

erd-2.1

Caenorhabditis elegans

Predicted to enable ER retention sequence binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cis-Golgi network and endoplasmic reticulum. Expressed in head and tail. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Is an ortholog of human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2).