Bma-ccm-3

Brugia malayi

Enriched in reproductive tract based on proteomic studies. Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Programmed cell death protein 10 and Protein of unknown function (DUF1241). Is an ortholog of C. elegans ccm-3. In C. elegans, ccm-3 is involved in several processes, including positive regulation of GTPase activity; positive regulation of endocytic recycling; and regulation of Golgi organization.

Bma-her-1

Brugia malayi

Is predicted to encode a protein with the following domains: Her-1 superfamily; Protein Her-1; Her-1, C-terminal; and Caenorhabditis elegans Her-1. Is an ortholog of C. elegans her-1. In C. elegans, her-1 is involved in male sex determination.

Bm3240

Brugia malayi

Is predicted to encode a protein with the following domains: Thrombospondin type-1 domain-containing protein 1; Thrombospondin type 1 domain; Thrombospondin type-1 (TSP1) repeat superfamily; and Thrombospondin type-1 (TSP1) repeat. Is an ortholog of C. elegans F09F9.4.

Bm3349

Brugia malayi

Is predicted to encode a protein with the following domains: Dynein light chain Tctex-1 like; Tctex-1 family; and Tctex-1-like superfamily. Is an ortholog of O. volvulus Ovo-dylt-1.

Bm2629

Brugia malayi

Is predicted to encode a protein with the following domains: Thrombospondin type 1 domain; Thrombospondin type-1 (TSP1) repeat superfamily; and Thrombospondin type-1 (TSP1) repeat.

Bma-blos-1

Brugia malayi

Predicted to be part of BLOC-1 complex. Is an ortholog of C. elegans blos-1. In C. elegans, blos-1 is involved in endosomal transport.

Bma-npa-1

Brugia malayi

Is predicted to encode a protein with the following domains: DVA-1 superfamily; Polyprotein allergen, nematode; and Nematode polyprotein allergen ABA-1. Is an ortholog of C. elegans npa-1.

Bma-pacs-1

Brugia malayi

Is predicted to encode a protein with the following domains: PACS-1 cytosolic sorting protein and Phosphofurin acidic cluster sorting protein 1. Is an ortholog of C. elegans pacs-1.

Bm6172

Brugia malayi

Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity. Is an ortholog of C. elegans paf-1 and paf-2. In C. elegans, paf-1 is involved in lipid catabolic process.

Bma-hyls-1

Brugia malayi

Is predicted to encode a protein with the following domains: Hydrolethalus syndrome protein 1, C-terminal domain and Hydrolethalus syndrome protein 1 C-terminus. Is an ortholog of C. elegans hyls-1. In C. elegans, hyls-1 is involved in cilium assembly and foraging behavior.