algn-12

Caenorhabditis elegans

Predicted to enable alpha-1,6-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ig. Is an ortholog of human ALG12 (ALG12 alpha-1,6-mannosyltransferase).

alh-12

Caenorhabditis elegans

Predicted to enable 4-trimethylammoniobutyraldehyde dehydrogenase activity and aminobutyraldehyde dehydrogenase (NAD+) activity. Is an ortholog of human ALDH9A1 (aldehyde dehydrogenase 9 family member A1).

chil-12

Caenorhabditis elegans

Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane.

daf-12

Caenorhabditis elegans

Enables nuclear receptor activity; sequence-specific DNA binding activity; and steroid hormone binding activity. Involved in several processes, including determination of adult lifespan; heat acclimation; and positive regulation of dauer larval development. Located in nucleus. Expressed in several structures, including gonad; neurons; pharyngeal muscle cell; somatic gonad precursor; and vulva. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; and carcinoma (multiple). Is an ortholog of human VDR (vitamin D receptor).

dhhc-12

Caenorhabditis elegans

Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in head neurons and tail neurons.

dmsr-12

Caenorhabditis elegans

Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in CEMDL and CEMDR.

fbxb-12

Caenorhabditis elegans

Is affected by several genes including cyc-1; rsr-2; and drh-3 based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; indole; and stavudine based on RNA-seq and microarray studies.

gly-12

Caenorhabditis elegans

Enables alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Involved in protein N-linked glycosylation. Located in perinuclear region of cytoplasm. Expressed in body wall musculature; ganglia; hypodermis; and intestine. Is an ortholog of human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase).

idpp-12

Caenorhabditis elegans

Expressed in pm8.

inx-12

Caenorhabditis elegans

Predicted to enable gap junction hemi-channel activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in gap junction and plasma membrane. Expressed in several structures, including head ganglion; interfacial epithelial cell; neurons; posterior lateral ganglion; and tail hypodermis.