Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including mrps-5; sin-3; and sir-2.1 based on RNA-seq and microarray studies.
Enriched in AWCL based on single-cell RNA-seq studies. Is affected by several genes including glp-1; sin-3; and chd-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies.
Is affected by several genes including dpy-21; rnp-6; and sin-3 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.
Enriched in NSM based on tiling array studies. Is affected by several genes including rsr-2; sin-3; and chd-3 based on tiling array and RNA-seq studies. Is affected by resveratrol based on microarray studies.
Enriched in ABaraapapp; ABaraapppp; intestine; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including sin-3; sir-2.1; and egl-43 based on RNA-seq and microarray studies.
Contributes to histone deacetylase activity. Involved in several processes, including cell fate specification; nematode male tail mating organ morphogenesis; and vulval development. Acts upstream of or within defense response to other organism and response to endoplasmic reticulum stress. Predicted to be located in chromatin. Predicted to be part of Sin3-type complex. Expressed in CEP; inner labial neurons; ray structural cell; socket cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in Huntington's disease and chromosome 15q24 deletion syndrome. Is an ortholog of human SIN3A (SIN3 transcription regulator family member A) and SIN3B (SIN3 transcription regulator family member B).