- K02F3.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA replication and double-strand break repair via homologous recombination. Predicted to be located in chromosome and cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and pancreatic cancer. Is an ortholog of human RECQL (RecQ like helicase).
- cka-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables choline kinase activity. Involved in CDP-choline pathway. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha).
- Sema4b [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a gene trap allele exhibit normal cerebellar morphology. Mice homozygous for a knock-out allele exhibit enhanced memory response by way of increased IgE and IgG1 serum levels. [provided by MGI curators]
- Cal6 [Search on AGR]
Mus musculus PHENOTYPE: Mice heterozygous for this spontaneous mutation exhibit a very curly coat and kinked vibrissae at 3 weeks of age. With age, the coat of mutant mice becomes straighter but appears to be rubbed the wrong way, while the vibrissae appear less kinked. [provided by MGI curators]
- atf-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in hydrogen sulfide biosynthetic process and positive regulation of gene expression. Located in nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is an ortholog of human ATF4 (activating transcription factor 4) and ATF5 (activating transcription factor 5).
- fws [Search on AGR]
Drosophila melanogaster four way stop (fws) encodes a protein localised to the Golgi apparatus and involved in several aspects of spermatogenesis. Loss of function of fws causes failure of cleavage furrow ingression in dividing spermatocytes, as well as failure of cell elongation and disruption of the Golgi-based acroblast during spermatid differentiation
- cogc-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be part of Golgi transport complex. Expressed in gonad. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIi. Is an ortholog of human COG5 (component of oligomeric golgi complex 5).