C28H8.3

Caenorhabditis elegans

Predicted to enable several functions, including ATP binding activity; helicase activity; and nucleic acid binding activity. Predicted to be located in cytoplasm. Is an ortholog of human DDX60 (DExD/H-box helicase 60) and DDX60L (DExD/H-box 60 like).

Y52B11A.3

Caenorhabditis elegans

Predicted to enable cytochrome-b5 reductase activity, acting on NAD(P)H and metal ion binding activity.

garr-1

Caenorhabditis elegans

Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in snoRNA guided rRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Is an ortholog of human GAR1 (GAR1 ribonucleoprotein).

srh-305

Caenorhabditis elegans

Is affected by clk-1; etr-1; and fmi-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Nematode receptor-like serpentine class H; Serpentine type 7TM GPCR chemoreceptor Srh; and 7TM GPCR, serpentine receptor class h (Srh).

Y48A5A.1

Caenorhabditis elegans

Predicted to enable unfolded protein binding activity. Predicted to be involved in box H/ACA snoRNP assembly. Predicted to be located in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in dystonia 35, childhood-onset. Is an ortholog of human SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor).

vha-18

Caenorhabditis elegans

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Is an ortholog of human ATP6V1H (ATPase H+ transporting V1 subunit H).

srh-228

Caenorhabditis elegans

Is affected by several genes including etr-1; csr-1; and mir-34 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nematode receptor-like serpentine class H; Serpentine type 7TM GPCR chemoreceptor Srh; and 7TM GPCR, serpentine receptor class h (Srh).

rnh-1.1

Caenorhabditis elegans

Enables RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer.

catp-3

Caenorhabditis elegans

Predicted to enable P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in stomach cancer. Is an ortholog of human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit) and ATP4A (ATPase H+/K+ transporting subunit alpha).

Y48A6B.3

Caenorhabditis elegans

Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in rRNA pseudouridine synthesis and snRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 2. Is an ortholog of human NHP2 (NHP2 ribonucleoprotein).