Pogz

Rattus norvegicus

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in kinetochore assembly; mitotic sister chromatid cohesion; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within with a positive effect on double-strand break repair via homologous recombination. Predicted to be located in several cellular components, including chromatin; ciliary basal body; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in White-Sutton syndrome. Orthologous to human POGZ (pogo transposable element derived with ZNF domain); INTERACTS WITH 2,6-dinitrotoluene; amitrole; bisphenol A.