Predicted to enable metal ion binding activity and nucleic acid binding activity. Predicted to be involved in kinetochore assembly and mitotic sister chromatid cohesion. Predicted to act upstream of or within with a positive effect on double-strand break repair via homologous recombination. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of chromatin. Human ortholog(s) of this gene implicated in White-Sutton syndrome. Orthologous to human POGZ (pogo transposable element derived with ZNF domain); INTERACTS WITH 2,6-dinitrotoluene; amitrole; bisphenol A.
ADIG/SMAF1 is an adipocyte-specific protein that plays a role in adipocyte differentiation (Kim et al., 2005 [PubMed 15567149]; Hong et al., 2005 [PubMed 16132694]).[supplied by OMIM, Mar 2008]
The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010]
Is predicted to encode a protein with the following domains: ET repeat and ET module. Is an ortholog of C. elegans gfi-1. In C. elegans, gfi-1 is involved in chromatin remodeling.