Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in kinetochore assembly; mitotic sister chromatid cohesion; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within with a positive effect on double-strand break repair via homologous recombination. Predicted to be located in several cellular components, including chromatin; ciliary basal body; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in White-Sutton syndrome. Orthologous to human POGZ (pogo transposable element derived with ZNF domain); INTERACTS WITH 2,6-dinitrotoluene; amitrole; bisphenol A.
ADIG/SMAF1 is an adipocyte-specific protein that plays a role in adipocyte differentiation (Kim et al., 2005 [PubMed 15567149]; Hong et al., 2005 [PubMed 16132694]).[supplied by OMIM, Mar 2008]
The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010]
Is predicted to encode a protein with the following domains: ET module and ET repeat. Is an ortholog of C. elegans gfi-1. In C. elegans, gfi-1 is involved in chromatin remodeling.