Rbmxl1 [Search on AGR]
Rattus norvegicus Enables RNA binding activity. Involved in protein-containing complex assembly and regulation of mRNA splicing, via spliceosome. Part of supraspliceosomal complex. Human ortholog(s) of this gene implicated in X-linked mental retardation Gustavson type and syndromic X-linked intellectual disability Shashi type. Orthologous to human RBMXL1 (RBMX like 1) and RBMX (RNA binding motif protein X-linked); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; fipronil.
Rbmx [Search on AGR]
Rattus norvegicus Enables single-stranded RNA binding activity. Involved in mRNA splice site recognition; positive regulation of DNA-templated transcription; and regulation of postsynapse organization. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in X-linked mental retardation Gustavson type and syndromic X-linked intellectual disability Shashi type. Orthologous to several human genes including RBMX (RNA binding motif protein X-linked); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.