rpsa-1

Caenorhabditis elegans

Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal small subunit assembly. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Expressed in tail. Is an ortholog of human RPSA (ribosomal protein SA).

PGRP-SA

Drosophila melanogaster

Peptidoglycan recognition protein SA (PGRP-SA) encodes a secreted protein that mediates Toll pathway activation during bacterial infection. It binds to peptidoglycans and, together with the product of GNBP1, activates the serine protease encoded by modSP.

Rpsa-ps4

Rattus norvegicus

Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal small subunit assembly. Predicted to be part of cytosolic small ribosomal subunit. Orthologous to human RPSA (ribosomal protein SA) and RPSA2 (ribosomal protein SA 2).

fah-1

Caenorhabditis elegans

Predicted to enable fumarylacetoacetase activity. Predicted to be involved in L-phenylalanine catabolic process; homogentisate catabolic process; and tyrosine catabolic process. Expressed in hypodermis. Used to study tyrosinemia type I. Human ortholog(s) of this gene implicated in tyrosinemia type I. Is an ortholog of human FAH (fumarylacetoacetate hydrolase).

cpi-2

Caenorhabditis elegans

Enables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C).

sa

Drosophila melanogaster

spermatocyte arrest (sa) encodes a testis binding protein associated factor involved in control of the male meiotic cycle, gene expression regulation, and spermatid differentiation.

GNBP1

Drosophila melanogaster

Gram-negative bacteria binding protein 1 (GNBP1) encodes a hemolymphatic protein that participates together with the product of PGRP-SA in the activation of the Toll pathway by peptidoglycans, a cell-wall component of bacteria.

CJA41863

Caenorhabditis japonica

Is predicted to encode a protein with the following domain: Cohesin subunit Scc3/SA. Is an ortholog of C. elegans scc-3. In C. elegans, scc-3 is involved in chromosome organization; double-strand break repair involved in meiotic recombination; and regulation of DNA damage checkpoint.

CJA34650

Caenorhabditis japonica

Is predicted to encode a protein with the following domain: Cohesin subunit Scc3/SA. Is an ortholog of C. elegans scc-3. In C. elegans, scc-3 is involved in chromosome organization; double-strand break repair involved in meiotic recombination; and regulation of DNA damage checkpoint.

RPS0A

Saccharomyces cerevisiae

Ribosomal 40S subunit protein S0A; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2; RPS0A has a paralog, RPS0B, that arose from the whole genome duplication;