agt-2

Caenorhabditis elegans

Enriched in Q cell; germ line; neurons; and oocyte based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including atfs-1; hsf-1; and mrps-5 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies.

agt-1

Caenorhabditis elegans

Enables damaged DNA binding activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Involved in DNA alkylation repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); and high grade glioma (multiple). Is an ortholog of human MGMT (O-6-methylguanine-DNA methyltransferase).

Cre-agt-2

Caenorhabditis remanei

Is an ortholog of C. elegans agt-2.

Cjp-agt-2

Caenorhabditis japonica

Is an ortholog of C. elegans agt-2.

Cjp-agt-1

Caenorhabditis japonica

Predicted to enable catalytic activity. Predicted to be involved in DNA repair. Is an ortholog of C. elegans agt-1. In C. elegans, agt-1 is involved in DNA alkylation repair.

Cbr-agt-1

Caenorhabditis briggsae

Predicted to enable catalytic activity. Predicted to be involved in DNA repair. Is an ortholog of C. elegans agt-1. In C. elegans, agt-1 is involved in DNA alkylation repair.

Cre-agt-1

Caenorhabditis remanei

Predicted to enable catalytic activity. Predicted to be involved in DNA repair. Is an ortholog of C. elegans agt-1. In C. elegans, agt-1 is involved in DNA alkylation repair.

Cbn-agt-1

Caenorhabditis brenneri

Predicted to enable catalytic activity. Predicted to be involved in DNA repair. Is an ortholog of C. elegans agt-1. In C. elegans, agt-1 is involved in DNA alkylation repair.

CRE10797

Caenorhabditis remanei

Predicted to enable methylated-DNA-[protein]-cysteine S-methyltransferase activity. Predicted to be involved in DNA repair. Is an ortholog of C. elegans agt-1. In C. elegans, agt-1 is involved in DNA alkylation repair.

CRE15855

Caenorhabditis remanei

Predicted to enable methylated-DNA-[protein]-cysteine S-methyltransferase activity. Predicted to be involved in DNA repair. Is an ortholog of C. elegans agt-1. In C. elegans, agt-1 is involved in DNA alkylation repair.