Predicted to enable zinc ion binding activity. Involved in lysosome organization. Predicted to be located in late endosome. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 6. Is an ortholog of human PLEKHM1 (pleckstrin homology and RUN domain containing M1).
Enables small GTPase binding activity. Involved in several processes, including dense core granule maturation; positive regulation of behavior; and regulation of transport. Located in several cellular components, including Golgi trans cisterna; neuronal cell body; and perinuclear region of cytoplasm. Expressed in uterus. Is an ortholog of human RUNDC1 (RUN domain containing 1).
Is predicted to encode a protein with the following domains: RUN domain; SH3 domain; SH3-like domain superfamily; Homeobox-like domain superfamily; and RUN domain superfamily.
Is predicted to encode a protein with the following domains: PDZ superfamily; PDZ domain; RUN domain superfamily; and RUN domain. Is an ortholog of C. elegans nrfl-1.
Enables protein kinase binding activity and scaffold protein binding activity. Involved in regulation of protein localization and synaptic vesicle localization. Located in neuron projection. Expressed in several structures, including hypodermis; intestine; motor neurons; muscle cell; and uterus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 61. Is an ortholog of human RUSC1 (RUN and SH3 domain containing 1) and RUSC2 (RUN and SH3 domain containing 2).
Is predicted to encode a protein with the following domains: RUN domain; PH-like domain superfamily; PDZ superfamily; Phosphotyrosine interaction domain (PTB/PID); PTB/PI domain; and RUN domain superfamily.
Is predicted to encode a protein with the following domains: RUN domain; PH-like domain superfamily; PH domain; Pleckstrin homology domain; and RUN domain superfamily. Is an ortholog of C. elegans T10B10.3.