aps-1

Caenorhabditis elegans

Involved in apical protein localization. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of AP-1 adaptor complex. Human ortholog(s) of this gene implicated in MEDNIK syndrome; psoriasis 15; and syndromic X-linked intellectual disability 5. Is an ortholog of human AP1S1 (adaptor related protein complex 1 subunit sigma 1) and AP1S2 (adaptor related protein complex 1 subunit sigma 2).

W08F4.3

Caenorhabditis elegans

Predicted to be located in endoplasmic reticulum. Expressed in tail. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and autosomal recessive distal hereditary motor neuronopathy 2. Is an ortholog of human SIGMAR1 (sigma non-opioid intracellular receptor 1).

aps-3

Caenorhabditis elegans

Predicted to be involved in vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human AP3S1 (adaptor related protein complex 3 subunit sigma 1) and AP3S2 (adaptor related protein complex 3 subunit sigma 2).

YLL053C

Saccharomyces cerevisiae

Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin

CJA43146

Caenorhabditis japonica

Predicted to enable DNA binding activity; DNA-binding transcription activator activity; and sigma factor activity. Predicted to be involved in DNA-templated transcription initiation.

CRE09945

Caenorhabditis remanei

Predicted to enable DNA binding activity and sigma factor activity. Predicted to be involved in DNA-templated transcription initiation and regulation of DNA-templated transcription.

CJA14998

Caenorhabditis japonica

Is predicted to encode a protein with the following domains: Helicase Helix-turn-helix domain; RNA polymerase sigma factor, region 3/4-like; and Helix-turn-helix domain.

AP-2

Drosophila melanogaster

Adaptor Protein complex 2, sigma subunit (AP-2sigma) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization.

Rpf1

Saccharomyces cerevisiae

Protein involved in assembly and export of the large ribosomal subunit; nucleolar protein; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA

BRX1

Saccharomyces cerevisiae

Nucleolar protein; constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif