T13G4.4

Caenorhabditis elegans

Predicted to enable S-adenosylmethionine-homocysteine S-methyltransferase activity. Predicted to be involved in S-methylmethionine cycle and methionine biosynthetic process.

gst-35

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

W10C8.4

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

gst-34

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

msra-1

Caenorhabditis elegans

Enables L-methionine:thioredoxin-disulfide S-oxidoreductase activity and peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in cytoplasm. Expressed in hypodermis and neurons. Is an ortholog of human MSRA (methionine sulfoxide reductase A).

Uba1

Mus musculus

PHENOTYPE: Male mice hemozygous for a null allele exhibit peri-implantation lethality. [provided by MGI curators]

slc-25A26

Caenorhabditis elegans

Enables S-adenosyl-L-methionine transmembrane transporter activity. Involved in mitochondrial S-adenosyl-L-methionine transmembrane transport. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Is an ortholog of human SLC25A26 (solute carrier family 25 member 26).

Orc1

Mus musculus

PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete peri-implantation lethality. [provided by MGI curators]

Haus3

Mus musculus

PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit pre- or peri-implantation lethality. [provided by MGI curators]

ahcy-1

Caenorhabditis elegans

Predicted to enable adenosylhomocysteinase activity. Predicted to be involved in S-adenosylhomocysteine catabolic process and S-adenosylmethionine cycle. Predicted to be located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm and hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Is an ortholog of human AHCY (adenosylhomocysteinase).