- pain [Search on AGR]
Drosophila melanogaster painless (pain) encodes a non-selective cation channel in the TRPA family that is required for the detection of noxious heat and mechanical stimuli.
- Frmpd4 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased inflammation-induced pain and thermal pain in a chronic pain model. [provided by MGI curators]
- Tmem45b [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a null allele exhibit reduced long-lasting mechanical pain hypersensitivity in a CFA-induced inflammatory pain model or following surgical tissue incision. [provided by MGI curators]
- NGF-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH Charcot-Marie-Tooth disease; Congenital Pain Insensitivity; genetic disease
- Scn10a [Search on AGR]
Mus musculus PHENOTYPE: Homozygotes for a targeted null mutation exhibit impaired perception of pain. Mice homozygous or heterozygous for an ENU-induced allele exhibit a catalepsy phenotype following scruffing and increased sensitivity to cold pain. [provided by MGI curators]
- SCN1A-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH Abnormality of pain sensation; absence epilepsy; Acute episodes of neuropathic symptoms
- Sema6c [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a targeted mutation display a decrease in pain threshold. [provided by MGI curators]
- tmgc38 [Search on AGR]
Mus musculus PHENOTYPE: Homozygous mice exhibit hypoalgesia to thermal and mechanical pain stimuli. [provided by MGI curators]
- Kcns1 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a conditional allele activated in DRG exhibit increased sensitivity to mechanical stimulation prior to and following neuropathic pain induction and cold nociception following neuropathic pain induction, and increased performance on a rotarod. [provided by MGI curators]
- B3gnt3 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a targeted mutation display increases in thermal pain sensation. [provided by MGI curators]