C29F3.7

Caenorhabditis elegans

Involved in innate immune response. Located in membrane raft.

C14C6.5

Caenorhabditis elegans

Involved in innate immune response.

F35E12.10

Caenorhabditis elegans

Predicted to be involved in innate immune response. Located in membrane raft.

irg-6

Caenorhabditis elegans

Involved in response to gamma radiation.

clec-4

Caenorhabditis elegans

Acts upstream of or within with a positive effect on feeding behavior. Expressed in amphid neurons; int1DL; int1DR; int1VL; and int1VR.

K08D8.5

Caenorhabditis elegans

Involved in innate immune response and response to gamma radiation. Expressed in head neurons; intestine; and rectal gland cell.

irg-4

Caenorhabditis elegans

Involved in defense response to Gram-negative bacterium and innate immune response. Expressed in head neurons and intestine.

Bub1

Drosophila melanogaster

Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens.

Lysmd3

Mus musculus

PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile with normal response to a range of pathogens. [provided by MGI curators]

Ifng

Mus musculus

PHENOTYPE: Mutants show immune system abnormalities including decreased inflammatory response in one line, and uncontrolled splenocyte proliferation and susceptibility to intracellular pathogens in another. [provided by MGI curators]