eif-3.D

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in pharynx. Is an ortholog of human EIF3D (eukaryotic translation initiation factor 3 subunit D).

eif-3.K

Caenorhabditis elegans

Predicted to enable RNA binding activity and ribosome binding activity. Predicted to contribute to translation initiation factor activity. Involved in positive regulation of apoptotic process. Located in cytoplasm. Expressed in several structures, including embryonic cell and germ line. Is an ortholog of human EIF3K (eukaryotic translation initiation factor 3 subunit K).

eif-3.E

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in nucleus. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3E (eukaryotic translation initiation factor 3 subunit E).

eif-3.C

Caenorhabditis elegans

Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3C (eukaryotic translation initiation factor 3 subunit C) and EIF3CL (eukaryotic translation initiation factor 3 subunit C like).

eif-3.G

Caenorhabditis elegans

Enables mRNA 5'-UTR binding activity. Involved in positive regulation of translation. Located in cytoplasm. Expressed in germ line and somatic cell. Is an ortholog of human EIF3G (eukaryotic translation initiation factor 3 subunit G).

egl-45

Caenorhabditis elegans

Predicted to enable mRNA binding activity and translation regulator activity. Predicted to contribute to translation initiation factor activity. Involved in egg-laying behavior and embryo development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 complex, eIF3m; and multi-eIF complex. Expressed in neurons. Is an ortholog of human EIF3A (eukaryotic translation initiation factor 3 subunit A).

eif-6

Caenorhabditis elegans

Predicted to enable ribosomal large subunit binding activity. Involved in miRNA-mediated post-transcriptional gene silencing. Predicted to be located in cytosol and nucleus. Used to study obesity. Is an ortholog of human EIF6 (eukaryotic translation initiation factor 6).

eif-1.A

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human EIF1AX (eukaryotic translation initiation factor 1A X-linked) and EIF1AY (eukaryotic translation initiation factor 1A Y-linked).

Y71G12B.10

Caenorhabditis elegans

Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in L-leucine catabolic process and ketone body biosynthetic process. Used to study 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Human ortholog(s) of this gene implicated in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).

ZK909.3

Caenorhabditis elegans

Predicted to enable guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity. Is an ortholog of human HDDC3 (HD domain containing 3).