bar-1

Caenorhabditis elegans

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coactivator activity. Involved in several processes, including nematode larval development; reproductive behavior; and response to stress. Located in several cellular components, including adherens junction; cytosol; and nucleus. Expressed in several structures, including gonad; intestine; and vulva.

C14A6.9

Caenorhabditis elegans

Is affected by several genes including wdr-5.1; bar-1; and daf-16 based on microarray and RNA-seq studies. Is affected by allantoin based on microarray studies.

T12A7.9

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including eri-1; dpy-21; and ogt-1 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily.

ndrr-1

Caenorhabditis elegans

Predicted to be involved in signal transduction. Located in striated muscle dense body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D and glioblastoma. Is an ortholog of human NDRG1 (N-myc downstream regulated 1); NDRG2 (NDRG family member 2); and NDRG3 (NDRG family member 3).

ndrr-2

Caenorhabditis elegans

Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D and glioblastoma. Is an ortholog of human NDRG1 (N-myc downstream regulated 1); NDRG2 (NDRG family member 2); and NDRG4 (NDRG family member 4).

M04F3.5

Caenorhabditis elegans

Predicted to enable actin binding activity and phospholipid binding activity. Involved in cell projection assembly and membrane organization. Located in cytoplasmic side of plasma membrane and filopodium. Human ortholog(s) of this gene implicated in intellectual developmental disorder with ocular anomalies and distinctive facial features. Is an ortholog of human MTSS2 (MTSS I-BAR domain containing 2).

axl-1

Caenorhabditis elegans

Enables protein kinase binding activity. Involved in axon guidance and negative regulation of Wnt signaling pathway.

W03B1.3

Caenorhabditis elegans

Enriched in OLL; PVD; seam cell; and tail precursor cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including cua-1; nuo-6; and atfs-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily.

Y47D3A.31

Caenorhabditis elegans

Enriched in germ line; intestine; and sperm based on single-cell RNA-seq and microarray studies. Is affected by several genes including mut-16; qui-1; and cua-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including ethanol; tryptophan; and methylmercury hydroxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily.

Y37F4.1

Caenorhabditis elegans

Enriched in neurons; vulval muscle; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including mut-16; qui-1; and atfs-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including D-glucose; Sodium Chloride; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily.