Cd300lb

Homo sapiens

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008]

Tada1

Homo sapiens

TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]

Supt7l

Homo sapiens

SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]

vab-10

Caenorhabditis elegans

Predicted to enable actin filament binding activity and structural molecule activity. Involved in epidermis morphogenesis. Located in apical plasma membrane; basal plasma membrane; and hemidesmosome. Expressed in several structures, including gonad; intestinal lumen; nerve ring; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex; hereditary sensory and autonomic neuropathy type 6; and lissencephaly 9 with complex brainstem malformation. Is an ortholog of human DST (dystonin).

Dst

Rattus norvegicus

Predicted to enable several functions, including integrin binding activity; microtubule plus-end binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including cytoskeleton organization; hemidesmosome assembly; and maintenance of cell polarity. Predicted to act upstream of or within axonogenesis and retrograde axonal transport. Predicted to be located in several cellular components, including cytoskeleton; endoplasmic reticulum; and nucleus. Predicted to be active in several cellular components, including focal adhesion; hemidesmosome; and type III intermediate filament. Predicted to colocalize with intermediate filament. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex and hereditary sensory and autonomic neuropathy type 6. Orthologous to human DST (dystonin); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Stag2

Rattus norvegicus

Predicted to enable chromatin binding activity. Predicted to be involved in mitotic spindle assembly and sister chromatid cohesion. Predicted to act upstream of or within stem cell population maintenance. Predicted to be located in mitotic spindle pole and nuclear lumen. Predicted to be part of mitotic cohesin complex. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in Holoprosencephaly 13, X-linked and Mullegama-Klein-Martinez syndrome. Orthologous to human STAG2 (STAG2 cohesin complex component); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.