lpin-1

Caenorhabditis elegans

Predicted to enable phosphatidate phosphatase activity and transcription coactivator activity. Involved in several processes, including endomembrane system organization; macromolecule localization; and nematode larval development. Located in endoplasmic reticulum; nuclear envelope; and nucleoplasm. Expressed in head neurons and hypodermis. Used to study obesity. Human ortholog(s) of this gene implicated in chronic recurrent multifocal osteomyelitis and morbid obesity. Is an ortholog of human LPIN2 (lipin 2).